Inusual localización de un tumor inusual. Comunicación breve de un caso
PDF

Palabras clave

Adenocarcinoma de células caliciformes
carcinoma de células caliciformes
carcinoide mucinoso Goblet cell adenocarcinoma
goblet cell carcinoma
mucinous carcinoid

Cómo citar

Lagos, J., & Duarte, A. (2022). Inusual localización de un tumor inusual. Comunicación breve de un caso. Archivos De Patologia, 3(2), 62–67. https://doi.org/10.47579/AP.v3.i2.0093

Resumen

El adenocarcinoma de células caliciformes o goblet cell carcinoma, es una neoplasia poco frecuente, reconocida por la OMS, que característicamente presenta componente mixto: exocrino y endocrino. Es un tumor casi exclusivo del apéndice cecal, pero se han reportado situaciones en las que surge en otros segmentos del tubo digestivo. Se presenta el caso de un hombre de 86 años con adenocarcinoma de células caliciformes extrapendicular en colon derecho. El estudio morfológico del apéndice cecal no demostró neoplasia. Se revisa la literatura referente a esta infrecuente neoplasia.

https://doi.org/10.47579/AP.v3.i2.0093
PDF

Citas

Wang H, Dhall D. Goblet or Signet Ring Cells That is the Question. Adv Anat Pathol. 2009;16:247-54.

Zhang K, Meyerson C, Kassardjian A, Westbrook LM, Zheng W, Wang HL. Goblet Cell Carcinoid/Carcinoma: An Update. Adv Anat Pathol. 2019;26:75-83.

Al-Zawi A, Khan K, Shah A, Asaad A, Salter V, Barron M, et al. Colonic Goblet Cell Carcinoid: Rarity of a Rarity! A Case Report and Review of Literature. Chirurgia. 2020;115:102-11.

Jang K, Park H, Noh S, Lee H, Lee M. Adenocarcinoma ex-goblet cell carcinoid of the ascending colon concurrent with conventional adenocarcinoma. Pathology. 2018;50:789-92.

Olsen I, Holt N, Langer S, Hasselby JP, Grønbæk H, Hillingsø J, et al. Goblet Cell Carcinoids: Characteristics of a Danish Cohort of 83 Patients. PloS ONE. 2015;10(2):e0117627. https://doi.org/10.1371/journal.pone.0117627

Wen K, Hale G, Shafizadeh N, Hosseini M, Huang A, Kakar S. Appendiceal goblet cell carcinoid: Common errors in staging and clinical interpretation with a proposal for an improved terminology. Human Pathology. 2017;65:187-93.

Reid M, Basturk O, Shaib W, Xue Y, Balci S, Choi H-J, et al. Adenocarcinoma ex goblet cell carcinoid (appendicealtype cript cell adenocarcinoma) is a morphologically distinct entity with highly aggressive behavior and frecuent association with peritoneal/intra-abdominal dissemination: An analysis of 77 cases. Modern Pathology. 2016;29:1243-53.

Wang Y, Li Y, Ke T. Adenocarcinoma Ex Goblet Cell Carcinoid of Appendix Two Case Reports. Case Reports in Pathology. 2017;2017:5930978. https://doi.org/10.1155/2017/5930978

Misdraji J, Carr NJ, Pai RK. Appendiceal goblet cell adenocarcinoma. En: Digestive System Tumours. WHO Classification of Tumours. 5th ed. Lyon: WHO Classification of Tumours Editorial Board; 2019. p. 149-151.

Knnop K, Newberry R. Goblet Cells: Multifaceted players in immnunity at mucosal surfaces. Mucosa Immunology. 2018;11:1551-7. https://doi.org/10.1038/s41385-018-0039-y

Nonaka D, Papaxoinis G, Lamarca A, Fulford P, Valle J, Chakrabarty B. A study of appendiceal crypt cell adenocarcinoma (so called-goblet cell carcinoid and its related adenocarcinoma). Human Pathology. 2018;72:18-27.

Maedler C, Arnason T, Dorren A, Sapp H, Castonguay M, Murphy J, et al. Goblet cell carcinoid of the appendix-An interobserver variability study using two proposed classification systems. Annals of Diagnostic Pathology. 2018;32:51-5. https://doi.org/10.1016/j.anndiagpath.2017.11.001

Yang C, Sun L, Zhang L, Zhou L, Niu D, Cao W, et al. SATB2 Shows Different Profiles Between Appendiceal Adenocarcinomas Ex Goblet Cell Carcinoids and Appendiceal/Colorectal Conventional Adenocarcinomas: An Immunohistochemical Study with Comparison to CDX2. Gastroenterol Res. 2018;11(3):221-30. https://doi.org/10.14740/gr1015w

Borazanci E, Mills S, Kimbrough J, Doll N, Von Hoff D, Ramanathan RK. Potencial actionable targets in appendiceal cancer detected by immunohistochemistry, fluorescent in situ hybridization, and mutational analysis. J Gastrointest Oncol. 2017;8(1):164-72.

https://doi.org/10.21037/jgo.2017.01.14

Johncilla M, Stachler M, Misdraji J, Lisovsky M, Yozu M, Lindeman N, et al. Mutational landscape of goblet cell carcinoids and adenocarcinoma ex goblet cell carcinoids of the appendix is distinct from typical carcinoids and colorectal adenocarcinomas. Modern Pathology. 2018;31: 989-96. https://doi.org/10.1038/s41379-018-0003-0

Creative Commons License

Esta obra está bajo una licencia internacional Creative Commons Atribución-NoComercial-SinDerivadas 4.0.

Derechos de autor 2022 Archivos de Patologia

Descargas

Los datos de descargas todavía no están disponibles.